ST3GAL1-Associated Transcriptomic Program in Glioblastoma Tumor Growth, Invasion, and Prognosis

BACKGROUND: Cell surface sialylation is associated with tumor cell invasiveness in many cancers. Glioblastoma is the most malignant primary brain tumor and is highly infiltrative. ST3GAL1 sialyltransferase gene is amplified in a subclass of glioblastomas, and its role in tumor cell self-renewal rema...

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Vydáno v:J Natl Cancer Inst
Hlavní autoři: Chong, Yuk Kien, Sandanaraj, Edwin, Koh, Lynnette W. H., Thangaveloo, Moogaambikai, Tan, Melanie S. Y., Koh, Geraldene R. H., Toh, Tan Boon, Lim, Grace G. Y., Holbrook, Joanna D., Kon, Oi Lian, Nadarajah, Mahendran, Ng, Ivan, Ng, Wai Hoe, Tan, Nguan Soon, Lim, Kah Leong, Tang, Carol, Ang, Beng Ti
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4755447/
https://ncbi.nlm.nih.gov/pubmed/26547933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djv326
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