ST3GAL1-Associated Transcriptomic Program in Glioblastoma Tumor Growth, Invasion, and Prognosis

BACKGROUND: Cell surface sialylation is associated with tumor cell invasiveness in many cancers. Glioblastoma is the most malignant primary brain tumor and is highly infiltrative. ST3GAL1 sialyltransferase gene is amplified in a subclass of glioblastomas, and its role in tumor cell self-renewal rema...

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Publicat a:J Natl Cancer Inst
Autors principals: Chong, Yuk Kien, Sandanaraj, Edwin, Koh, Lynnette W. H., Thangaveloo, Moogaambikai, Tan, Melanie S. Y., Koh, Geraldene R. H., Toh, Tan Boon, Lim, Grace G. Y., Holbrook, Joanna D., Kon, Oi Lian, Nadarajah, Mahendran, Ng, Ivan, Ng, Wai Hoe, Tan, Nguan Soon, Lim, Kah Leong, Tang, Carol, Ang, Beng Ti
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4755447/
https://ncbi.nlm.nih.gov/pubmed/26547933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djv326
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