Metabolism of profenofos to 4-bromo-2-chlorophenol, a specific and sensitive exposure biomarker

Profenofos is a direct acting phosphorothioate organophosphorus (OP) pesticide capable of inhibiting β-esterases such as acetylcholinesterase, butyrylcholinesterase, and carboxylesterase. Profenofos is known to be detoxified to the biologically inactive metabolite, 4-bromo-2-chlorophenol (BCP); howe...

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Bibliographic Details
Published in:Toxicology
Main Authors: Dadson, Oswald A., Ellison, Corie A., Singleton, Steven T., Chi, Lai-Har, McGarrigle, Barbara P., Lein, Pamela J., Farahat, Fayssal M., Farahat, Taghreed, Olson, James R.
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4751995/
https://ncbi.nlm.nih.gov/pubmed/23415833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tox.2013.01.023
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