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The role of checkpoints in the treatment of GBM

Targeted immunotherapy is founded on the principle that augmentation of effector T cell activity in the tumor microenvironment can translate to tumor regression. Targeted checkpoint inhibitors in the form of agonist or antagonist monoclonal antibodies have come to the fore as a promising strategy to...

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Détails bibliographiques
Publié dans:J Neurooncol
Auteurs principaux: Kim, Jennifer E., Lim, Michael
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4750481/
https://ncbi.nlm.nih.gov/pubmed/25749875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-015-1747-8
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