Chemotherapy with BCNU in recurrent glioma: Analysis of clinical outcome and side effects in chemotherapy-naïve patients

BACKGROUND: To date, standardized strategies for the treatment of recurrent glioma are lacking. Chemotherapy with the alkylating agent BCNU (1,3-bis (2-chloroethyl)-1-nitroso-urea) is a therapeutic option even though its efficacy and safety, particularly the risk of pulmonary fibrosis, remains contr...

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Bibliographic Details
Published in:BMC Cancer
Main Authors: Jungk, Christine, Chatziaslanidou, Despina, Ahmadi, Rezvan, Capper, David, Bermejo, Justo Lorenzo, Exner, Janina, von Deimling, Andreas, Herold-Mende, Christel, Unterberg, Andreas
Format: Artigo
Language:Inglês
Published: BioMed Central 2016
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4748520/
https://ncbi.nlm.nih.gov/pubmed/26865253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2131-6
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