What links BRAF to the heart function? new insights from the cardiotoxicity of BRAF inhibitors in cancer treatment

The RAS-related signalling cascade has a fundamental role in cell. It activates differentiation and survival. It is particularly important one of its molecules, B-RAF. B-RAF has been a central point for research, especially in melanoma. Indeed, it lacked effective therapeutic weapons since the early...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Bronte, Enrico, Bronte, Giuseppe, Novo, Giuseppina, Bronte, Fabrizio, Bavetta, Maria Grazia, Re, Giuseppe Lo, Brancatelli, Giuseppe, Bazan, Viviana, Natoli, Clara, Novo, Salvatore, Russo, Antonio
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2015
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742127/
https://ncbi.nlm.nih.gov/pubmed/26431495
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