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Sex-dependent effects of developmental arsenic exposure on methylation capacity and methylation regulation of the glucocorticoid receptor system in the embryonic mouse brain

Previously we have shown that prenatal moderate arsenic exposure (50 ppb) disrupts glucocorticoid receptor (GR) programming and that these changes continue into adolescence in males. However, it was not clear what the molecular mechanisms were promoting these GR programming changes or if these chang...

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Bibliografiska uppgifter
I publikationen:Toxicol Rep
Huvudupphovsmän: Allan, Andrea M., Hafez, Alexander K., Labrecque, Matthew T., Solomon, Elizabeth R., Shaikh, M. Nabil, Zheng, Xianyun, Ali, Abdulmehdi
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741109/
https://ncbi.nlm.nih.gov/pubmed/26855884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxrep.2015.10.003
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