Sex-dependent effects of developmental arsenic exposure on methylation capacity and methylation regulation of the glucocorticoid receptor system in the embryonic mouse brain

Previously we have shown that prenatal moderate arsenic exposure (50 ppb) disrupts glucocorticoid receptor (GR) programming and that these changes continue into adolescence in males. However, it was not clear what the molecular mechanisms were promoting these GR programming changes or if these chang...

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Gepubliceerd in:Toxicol Rep
Hoofdauteurs: Allan, Andrea M., Hafez, Alexander K., Labrecque, Matthew T., Solomon, Elizabeth R., Shaikh, M. Nabil, Zheng, Xianyun, Ali, Abdulmehdi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741109/
https://ncbi.nlm.nih.gov/pubmed/26855884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxrep.2015.10.003
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