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Sex-dependent effects of developmental arsenic exposure on methylation capacity and methylation regulation of the glucocorticoid receptor system in the embryonic mouse brain

Previously we have shown that prenatal moderate arsenic exposure (50 ppb) disrupts glucocorticoid receptor (GR) programming and that these changes continue into adolescence in males. However, it was not clear what the molecular mechanisms were promoting these GR programming changes or if these chang...

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Détails bibliographiques
Publié dans:Toxicol Rep
Auteurs principaux: Allan, Andrea M., Hafez, Alexander K., Labrecque, Matthew T., Solomon, Elizabeth R., Shaikh, M. Nabil, Zheng, Xianyun, Ali, Abdulmehdi
Format: Artigo
Langue:Inglês
Publié: Elsevier 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741109/
https://ncbi.nlm.nih.gov/pubmed/26855884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxrep.2015.10.003
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