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Miglustat Reverts the Impairment of Synaptic Plasticity in a Mouse Model of NPC Disease

Niemann-Pick type C disease is an autosomal recessive storage disorder, characterized by abnormal sequestration of unesterified cholesterol within the late endolysosomal compartment of cells and accumulation of gangliosides and other sphingolipids. Progressive neurological deterioration and insurgen...

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Détails bibliographiques
Publié dans:Neural Plast
Auteurs principaux: D'Arcangelo, G., Grossi, D., Racaniello, M., Cardinale, A., Zaratti, A., Rufini, S., Cutarelli, A., Tancredi, V., Merlo, D., Frank, C.
Format: Artigo
Langue:Inglês
Publié: Hindawi Publishing Corporation 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4738957/
https://ncbi.nlm.nih.gov/pubmed/26885401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/3830424
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