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Miglustat Reverts the Impairment of Synaptic Plasticity in a Mouse Model of NPC Disease
Niemann-Pick type C disease is an autosomal recessive storage disorder, characterized by abnormal sequestration of unesterified cholesterol within the late endolysosomal compartment of cells and accumulation of gangliosides and other sphingolipids. Progressive neurological deterioration and insurgen...
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Publié dans: | Neural Plast |
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Auteurs principaux: | , , , , , , , , , |
Format: | Artigo |
Langue: | Inglês |
Publié: |
Hindawi Publishing Corporation
2016
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4738957/ https://ncbi.nlm.nih.gov/pubmed/26885401 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/3830424 |
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