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Precise assembly of complex beta sheet topologies from de novo designed building blocks
Design of complex alpha-beta protein topologies poses a challenge because of the large number of alternative packing arrangements. A similar challenge presumably limited the emergence of large and complex protein topologies in evolution. Here, we demonstrate that protein topologies with six and seve...
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| Udgivet i: | eLife |
|---|---|
| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
eLife Sciences Publications, Ltd
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4737653/ https://ncbi.nlm.nih.gov/pubmed/26650357 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.11012 |
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