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A Drosophila RNAi library modulates Hippo pathway-dependent tissue growth

Libraries of transgenic Drosophila melanogaster carrying RNA interference (RNAi) constructs have been used extensively to perform large-scale functional genetic screens in vivo. For example, RNAi screens have facilitated the discovery of multiple components of the Hippo pathway, an evolutionarily co...

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Publicat a:Nat Commun
Autors principals: Vissers, Joseph H.A., Manning, Samuel A., Kulkarni, Aishwarya, Harvey, Kieran F.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4735554/
https://ncbi.nlm.nih.gov/pubmed/26758424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10368
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