Genome-Wide Meta-Analysis of Cotinine Levels in Cigarette Smokers Identifies Locus at 4q13.2

Genome-wide association studies (GWAS) of complex behavioural phenotypes such as cigarette smoking typically employ self-report phenotypes. However, precise biomarker phenotypes may afford greater statistical power and identify novel variants. Here we report the results of a GWAS meta-analysis of le...

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Autori principali: Ware, Jennifer J., Chen, Xiangning, Vink, Jacqueline, Loukola, Anu, Minica, Camelia, Pool, Rene, Milaneschi, Yuri, Mangino, Massimo, Menni, Cristina, Chen, Jingchun, Peterson, Roseann E., Auro, Kirsi, Lyytikäinen, Leo-Pekka, Wedenoja, Juho, Stiby, Alexander I., Hemani, Gibran, Willemsen, Gonneke, Hottenga, Jouke Jan, Korhonen, Tellervo, Heliövaara, Markku, Perola, Markus, Rose, Richard J., Paternoster, Lavinia, Timpson, Nic, Wassenaar, Catherine A., Zhu, Andy Z. X., Davey Smith, George, T. Raitakari, Olli, Lehtimäki, Terho, Kähönen, Mika, Koskinen, Seppo, Spector, Timothy, Penninx, Brenda W. J. H., Salomaa, Veikko, Boomsma, Dorret I., Tyndale, Rachel F., Kaprio, Jaakko, Munafò, Marcus R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4735517/
https://ncbi.nlm.nih.gov/pubmed/26833182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20092
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