Serum concentrations of clarithromycin and rifampicin in pulmonary Mycobacterium avium complex disease: long-term changes due to drug interactions and their association with clinical outcomes

BACKGROUND: Concomitant use of clarithromycin (CAM) and rifampicin (RFP) for the treatment of pulmonary Mycobacterium avium complex (MAC) disease affects the systemic concentrations of both drugs due to CYP3A4–related interactions. To date, however, there has been no report that investigates the lon...

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Detalhes bibliográficos
Publicado no:J Pharm Health Care Sci
Main Authors: Shimomura, Hitoshi, Andachi, Sena, Aono, Takahiro, Kigure, Akira, Yamamoto, Yosuke, Miyajima, Atsushi, Hirota, Takashi, Imanaka, Keiko, Majima, Toru, Masuyama, Hidenori, Tatsumi, Koichiro, Aoyama, Takao
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4728759/
https://ncbi.nlm.nih.gov/pubmed/26819743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40780-015-0029-0
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