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MAP3K1 function is essential for cytoarchitecture of the mouse organ of Corti and survival of auditory hair cells
MAP3K1 is a serine/threonine kinase that is activated by a diverse set of stimuli and exerts its effect through various downstream effecter molecules, including JNK, ERK1/2 and p38. In humans, mutant alleles of MAP3K1 are associated with 46,XY sex reversal. Until recently, the only phenotype observe...
Zapisane w:
| Wydane w: | Dis Model Mech |
|---|---|
| Główni autorzy: | , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
The Company of Biologists
2015
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4728323/ https://ncbi.nlm.nih.gov/pubmed/26496772 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.023077 |
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