Mycobacterium Lysine ε-aminotransferase is a novel alarmone metabolism related persister gene via dysregulating the intracellular amino acid level

Bacterial persisters, usually slow-growing, non-replicating cells highly tolerant to antibiotics, play a crucial role contributing to the recalcitrance of chronic infections and treatment failure. Understanding the molecular mechanism of persister cells formation and maintenance would obviously insp...

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Vydáno v:Sci Rep
Hlavní autoři: Duan, Xiangke, Li, Yunsong, Du, Qinglin, Huang, Qinqin, Guo, Siyao, Xu, Mengmeng, Lin, Yanping, Liu, Zhidong, Xie, Jianping
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4726150/
https://ncbi.nlm.nih.gov/pubmed/26806099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19695
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