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Bispecific Antibody Affords Complete Post-Exposure Protection of Mice from Both Ebola (Zaire) and Sudan Viruses

Filoviruses (Ebola and Marburg) cause severe hemorrhagic fever. There are five species of ebolavirus; among these, the Ebola (Zaire) and Sudan viruses (EBOV and SUDV, respectively) are highly pathogenic and have both caused recurring, large outbreaks. However, the EBOV and SUDV glycoprotein (GP) seq...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Frei, Julia C., Nyakatura, Elisabeth K., Zak, Samantha E., Bakken, Russell R., Chandran, Kartik, Dye, John M., Lai, Jonathan R.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4725817/
https://ncbi.nlm.nih.gov/pubmed/26758505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19193
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