Structural basis for activation, assembly and membrane binding of ESCRT-III Snf7 filaments

The endosomal sorting complexes required for transport (ESCRTs) constitute hetero-oligomeric machines that catalyze multiple topologically similar membrane-remodeling processes. Although ESCRT-III subunits polymerize into spirals, how individual ESCRT-III subunits are activated and assembled togethe...

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Bibliographic Details
Published in:eLife
Main Authors: Tang, Shaogeng, Henne, W Mike, Borbat, Peter P, Buchkovich, Nicholas J, Freed, Jack H, Mao, Yuxin, Fromme, J Christopher, Emr, Scott D
Format: Artigo
Language:Inglês
Published: eLife Sciences Publications, Ltd 2015
Subjects:
Biophysics and Structural Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4720517/
https://ncbi.nlm.nih.gov/pubmed/26670543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.12548
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