A mouse model for adult cardiac-specific gene deletion with CRISPR/Cas9

Clustered regularly interspaced short palindromic repeats (CRISPR)-associated (Cas)9 genomic editing has revolutionized the generation of mutant animals by simplifying the creation of null alleles in virtually any organism. However, most current approaches with this method require zygote injection,...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Carroll, Kelli J., Makarewich, Catherine A., McAnally, John, Anderson, Douglas M., Zentilin, Lorena, Liu, Ning, Giacca, Mauro, Bassel-Duby, Rhonda, Olson, Eric N.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2016
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4720342/
https://ncbi.nlm.nih.gov/pubmed/26719419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1523918113
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