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Sulfate and thiosulfate inhibit oxalate transport via a dPrestin (Slc26a6)-dependent mechanism in an insect model of calcium oxalate nephrolithiasis

Nephrolithiasis is one of the most common urinary tract disorders, with the majority of kidney stones composed of calcium oxalate (CaOx). Given its prevalence (US occurrence 10%), it is still poorly understood, lacking progress in identifying new therapies because of its complex etiology. Drosophila...

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Detalhes bibliográficos
Publicado no:Am J Physiol Renal Physiol
Main Authors: Landry, Greg M., Hirata, Taku, Anderson, Jacob B., Cabrero, Pablo, Gallo, Christopher J. R., Dow, Julian A. T., Romero, Michael F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4719044/
https://ncbi.nlm.nih.gov/pubmed/26538444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00406.2015
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