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Fine-tuning citrate synthase flux potentiates and refines metabolic innovation in the Lenski evolution experiment

Evolutionary innovations that enable organisms to colonize new ecological niches are rare compared to gradual evolutionary changes in existing traits. We discovered that key mutations in the gltA gene, which encodes citrate synthase (CS), occurred both before and after Escherichia coli gained the ab...

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Bibliografiske detaljer
Udgivet i:eLife
Main Authors: Quandt, Erik M, Gollihar, Jimmy, Blount, Zachary D, Ellington, Andrew D, Georgiou, George, Barrick, Jeffrey E
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4718724/
https://ncbi.nlm.nih.gov/pubmed/26465114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.09696
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