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HBV cccDNA in patients’ sera as an indicator for HBV reactivation and an early signal of liver damage

AIM: To evaluate the covalently closed circle DNA (cccDNA) level of hepatitis B virus (HBV) in patients’ liver and sera. METHODS: HBV DNA was isolated from patients’ liver biopsies and sera. A sensitive real-time PCR method, which is capable of differentiation of HBV viral genomic DNA and cccDNA, wa...

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Detalhes bibliográficos
Publicado no:World J Gastroenterol
Main Authors: Chen, Ying, Sze, Johnny, He, Ming-Liang
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Inc 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4717084/
https://ncbi.nlm.nih.gov/pubmed/14695774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v10.i1.82
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