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The potential role for ocrelizumab in the treatment of multiple sclerosis: current evidence and future prospects
B cells play a central role in the pathogenesis in multiple sclerosis (MS), being involved in the activation of proinflammatory T cells, secretion of proinflammatory cytokines, and production of autoantibodies directed against myelin. Hence, the usage of B-cell-depleting monoclonal antibodies as the...
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Published in: | Ther Adv Neurol Disord |
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Main Authors: | , |
Format: | Artigo |
Language: | Inglês |
Published: |
SAGE Publications
2016
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4710102/ https://ncbi.nlm.nih.gov/pubmed/26788130 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1756285615601933 |
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