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The potential role for ocrelizumab in the treatment of multiple sclerosis: current evidence and future prospects

B cells play a central role in the pathogenesis in multiple sclerosis (MS), being involved in the activation of proinflammatory T cells, secretion of proinflammatory cytokines, and production of autoantibodies directed against myelin. Hence, the usage of B-cell-depleting monoclonal antibodies as the...

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Bibliographic Details
Published in:Ther Adv Neurol Disord
Main Authors: Sorensen, Per Soelberg, Blinkenberg, Morten
Format: Artigo
Language:Inglês
Published: SAGE Publications 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4710102/
https://ncbi.nlm.nih.gov/pubmed/26788130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1756285615601933
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