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Discovery of potential ALK inhibitors by virtual screening approach
Crizotinib is an anticancer drug used for the treatment of non-small cell lung cancer. Evidences available suggest that there is a development of an acquired resistance against crizotinib action due to the emergence of several mutations in the ALK gene. It is therefore necessary to develop potent an...
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| Published in: | 3 Biotech |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Springer Berlin Heidelberg
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4706832/ https://ncbi.nlm.nih.gov/pubmed/28330089 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13205-015-0336-z |
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