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A Flow Cytometric Clonogenic Assay Reveals the Single-Cell Potency of Doxorubicin

Standard cell proliferation assays use bulk media drug concentration to ascertain the potency of chemotherapeutic drugs; however, the relevant quantity is clearly the amount of drug actually taken up by the cell. To address this discrepancy, we have developed a flow cytometric clonogenic assay to co...

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Detalhes bibliográficos
Publicado no:J Pharm Sci
Main Authors: Maass, Katie F., Kulkarni, Chethana, Quadir, Mohiuddin A., Hammond, Paula T., Betts, Alison M., Wittrup, K. Dane
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4706798/
https://ncbi.nlm.nih.gov/pubmed/26344409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jps.24631
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