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Alectinib in RET-rearranged non-small cell lung cancer—Another progress in precision medicine?

RET fusions have been recognized as potential therapeutic targets in advanced non-small cell lung cancer. RET fusion proteins are detected in about 2% of lung adenocarcinomas. Alectinib, a second generation ALK inhibitor, was shown to block growth of cells with RET fusions. Thus alectinib should be...

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Bibliografske podrobnosti
izdano v:Transl Lung Cancer Res
Main Authors: Pirker, Robert, Filipits, Martin
Format: Artigo
Jezik:Inglês
Izdano: AME Publishing Company 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4700226/
https://ncbi.nlm.nih.gov/pubmed/26798590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3978/j.issn.2218-6751.2015.03.08
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