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Dual mTORC1/2 inhibition in a preclinical xenograft tumor model of endometrial cancer
OBJECTIVES: Up to 70% of endometrioid endometrial cancers carry PTEN gene deletions that can upregulate mTOR activity. Investigational mTOR kinase inhibitors may provide a novel therapeutic approach for these tumors. Using a xenograft tumor model of endometrial cancer, we assessed the activity of mT...
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| Vydáno v: | Gynecol Oncol |
|---|---|
| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4696930/ https://ncbi.nlm.nih.gov/pubmed/24316308 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2013.11.027 |
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