Transcriptome profiling reveals divergent expression shifts in brown and white adipose tissue from long-lived GHRKO mice

Mice lacking the growth hormone receptor (GHRKO) exhibit improved lifespan and healthspan due to loss of growth hormone signaling. Both the distribution and activity of brown and white adipose tissue (BAT and WAT) are altered in GHRKO mice, but the contribution of each tissue to age-related phenotyp...

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Pubblicato in:Oncotarget
Autori principali: Stout, Michael B., Swindell, William R., Zhi, Xu, Rohde, Kyle, List, Edward O., Berryman, Darlene E., Kopchick, John J., Gesing, Adam, Fang, Yimin, Masternak, Michal M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2015
Soggetti:
Research Paper: Gerotarget (Focus on Aging)
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4694946/
https://ncbi.nlm.nih.gov/pubmed/26436954
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