Transcriptome profiling reveals divergent expression shifts in brown and white adipose tissue from long-lived GHRKO mice

Mice lacking the growth hormone receptor (GHRKO) exhibit improved lifespan and healthspan due to loss of growth hormone signaling. Both the distribution and activity of brown and white adipose tissue (BAT and WAT) are altered in GHRKO mice, but the contribution of each tissue to age-related phenotyp...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Stout, Michael B., Swindell, William R., Zhi, Xu, Rohde, Kyle, List, Edward O., Berryman, Darlene E., Kopchick, John J., Gesing, Adam, Fang, Yimin, Masternak, Michal M.
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2015
Matèries:
Research Paper: Gerotarget (Focus on Aging)
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4694946/
https://ncbi.nlm.nih.gov/pubmed/26436954
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