GL-V9, a new synthetic flavonoid derivative, ameliorates DSS-induced colitis against oxidative stress by up-regulating Trx-1 expression via activation of AMPK/FOXO3a pathway

GL-V9, a new synthesized flavonoid derivative, has been reported to possess anti-cancer properties in our previous studies. Uncontrolled overproduction of reactive oxygen species (ROS) has been implicated in oxidative damage of inflammatory bowel disease (IBD). In this study, we aimed to investigate...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zhao, Yue, Sun, Yang, Ding, Youxiang, Wang, Xiaoping, Zhou, Yuxin, Li, Wenjun, Huang, Shaoliang, Li, Zhiyu, Kong, Lingyi, Guo, Qinglong, Lu, Na
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4694902/
https://ncbi.nlm.nih.gov/pubmed/26327408
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