A measles virus selectively blind to signaling lymphocytic activation molecule shows anti-tumor activity against lung cancer cells

Lung cancer cells, particularly those of non-small-cell lung cancer, are known to express Nectin-4. We previously generated a recombinant measles virus that uses Nectin-4 as its receptor but cannot bind its original principal receptor, signaling lymphocyte activation molecule (SLAM). This virus (rMV...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Fujiyuki, Tomoko, Yoneda, Misako, Amagai, Yosuke, Obayashi, Kunie, Ikeda, Fusako, Shoji, Koichiro, Murakami, Yoshinori, Sato, Hiroki, Kai, Chieko
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2015
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4694801/
https://ncbi.nlm.nih.gov/pubmed/26317644
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