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A Quick Phenotypic Neurological Scoring System for Evaluating Disease Progression in the SOD1-G93A Mouse Model of ALS
The SOD1-G93A transgenic mouse is the most widely used animal model of amyotrophic lateral sclerosis (ALS). At ALS TDI we developed a phenotypic screening protocol, demonstrated in video herein, which reliably assesses the neuromuscular function of SOD1-G93A mice in a quick manner. This protocol enc...
Shranjeno v:
izdano v: | J Vis Exp |
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Main Authors: | , , , , , |
Format: | Artigo |
Jezik: | Inglês |
Izdano: |
MyJove Corporation
2015
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4692639/ https://ncbi.nlm.nih.gov/pubmed/26485052 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/53257 |
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