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A Quick Phenotypic Neurological Scoring System for Evaluating Disease Progression in the SOD1-G93A Mouse Model of ALS

The SOD1-G93A transgenic mouse is the most widely used animal model of amyotrophic lateral sclerosis (ALS). At ALS TDI we developed a phenotypic screening protocol, demonstrated in video herein, which reliably assesses the neuromuscular function of SOD1-G93A mice in a quick manner. This protocol enc...

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Détails bibliographiques
Publié dans:J Vis Exp
Auteurs principaux: Hatzipetros, Theo, Kidd, Joshua D., Moreno, Andy J., Thompson, Kenneth, Gill, Alan, Vieira, Fernando G.
Format: Artigo
Langue:Inglês
Publié: MyJove Corporation 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4692639/
https://ncbi.nlm.nih.gov/pubmed/26485052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/53257
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