Prenatal and early life influences on epigenetic age in children: a study of mother–offspring pairs from two cohort studies

DNA methylation-based biomarkers of aging are highly correlated with actual age. Departures of methylation-estimated age from actual age can be used to define epigenetic measures of child development or age acceleration (AA) in adults. Very little is known about genetic or environmental determinants...

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Vydáno v:Hum Mol Genet
Hlavní autoři: Simpkin, Andrew J., Hemani, Gibran, Suderman, Matthew, Gaunt, Tom R., Lyttleton, Oliver, Mcardle, Wendy L., Ring, Susan M., Sharp, Gemma C., Tilling, Kate, Horvath, Steve, Kunze, Sonja, Peters, Annette, Waldenberger, Melanie, Ward-Caviness, Cavin, Nohr, Ellen A., Sørensen, Thorkild I. A., Relton, Caroline L., Smith, George Davey
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2016
Témata:
Association Studies Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4690495/
https://ncbi.nlm.nih.gov/pubmed/26546615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv456
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