Hypothesis: Induced angiogenesis after surgery in premenopausal node-positive breast cancer patients is a major underlying reason why adjuvant chemotherapy works particularly well for those patients

BACKGROUND: We suggest that surgical extirpation of primary breast cancer among other effects accelerates relapse for some premenopausal node-positive patients. These accelerated relapses occur within 10 months of surgery for untreated patients. The mechanism proposed is a stimulation of angiogenesi...

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Bibliografiske detaljer
Main Authors: Retsky, Michael, Bonadonna, Gianni, Demicheli, Romano, Folkman, Judah, Hrushesky, William, Valagussa, Pinuccia
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2004
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC468653/
https://ncbi.nlm.nih.gov/pubmed/15217504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr804
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