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Chemically induced DNA hypomethylation in breast carcinoma cells detected by the amplification of intermethylated sites
INTRODUCTION: Compromised patterns of gene expression result in genomic instability, altered patterns of gene expression and tumour formation. Specifically, aberrant DNA hypermethylation in gene promoter regions leads to gene silencing, whereas global hypomethylation events can result in chromosomal...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC468641/ https://ncbi.nlm.nih.gov/pubmed/15217500 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr799 |
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