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Population pharmacokinetics of unbound hydrocortisone in critically ill neonates and infants with vasopressor-resistant hypotension
OBJECTIVE: To determine the population pharmacokinetics of unbound hydrocortisone (HC) in critically ill neonates and infants receiving intravenous HC for treatment of vasopressor-resistant hypotension and to identify patient-specific sources of pharmacokinetic variability. DESIGN: Prospective obser...
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Publicado en: | Pediatr Crit Care Med |
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Autores principales: | , , , , |
Formato: | Artigo |
Lenguaje: | Inglês |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4682874/ https://ncbi.nlm.nih.gov/pubmed/24797719 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PCC.0000000000000152 |
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