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Epigenetic regulation of CDH1 exon 8 alternative splicing in gastric cancer
BACKGROUND: The tumor suppressor gene CDH1 is critical for intercellular adhesion. In our previous work, we reported a nonfunctional CDH1 transcript that lacks the final 83 base pairs of exon 8 (1054del83). In this work, we probed the role of histone epigenetic modifications as well as DNA methylati...
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| Pubblicato in: | BMC Cancer |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4682244/ https://ncbi.nlm.nih.gov/pubmed/26674321 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1983-5 |
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