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Epigenetic regulation of CDH1 exon 8 alternative splicing in gastric cancer
BACKGROUND: The tumor suppressor gene CDH1 is critical for intercellular adhesion. In our previous work, we reported a nonfunctional CDH1 transcript that lacks the final 83 base pairs of exon 8 (1054del83). In this work, we probed the role of histone epigenetic modifications as well as DNA methylati...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | BMC Cancer |
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| Κύριοι συγγραφείς: | , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
BioMed Central
2015
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4682244/ https://ncbi.nlm.nih.gov/pubmed/26674321 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1983-5 |
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