Epigenetic regulation of CDH1 exon 8 alternative splicing in gastric cancer

BACKGROUND: The tumor suppressor gene CDH1 is critical for intercellular adhesion. In our previous work, we reported a nonfunctional CDH1 transcript that lacks the final 83 base pairs of exon 8 (1054del83). In this work, we probed the role of histone epigenetic modifications as well as DNA methylati...

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Bibliographic Details
Published in:BMC Cancer
Main Authors: Li, Xiao-Wei, Shi, Bing-Yu, Yang, Qing-Lan, Wu, Jie, Wu, Hui-Min, Wang, Yu-Feng, Wu, Zhi-Jiao, Fan, Yi-Mei, Wang, Ya-Ping
Format: Artigo
Language:Inglês
Published: BioMed Central 2015
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4682244/
https://ncbi.nlm.nih.gov/pubmed/26674321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1983-5
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