IDENTIFICATION OF NOVEL POLYGLUTAMINE-EXPANDED AGGREGATION SPECIES IN SPINAL AND BULBAR MUSCULAR ATROPHY

Polyglutamine-repeat disorders are part of a larger family of neurodegenerative diseases characterized by protein misfolding and aggregation. In spinal and bulbar muscular atrophy (SBMA), polyglutamine expansion within the androgen receptor (AR) causes progressive debilitating muscular atrophy and l...

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Detalhes bibliográficos
Publicado no:Brain Res
Main Authors: Berger, Tamar R., Montie, Heather L., Jain, Pranav, Legleiter, Justin, Merry, Diane
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4681586/
https://ncbi.nlm.nih.gov/pubmed/26453288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2015.09.033
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