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Genetic factors affecting statin concentrations and subsequent myopathy: a HuGENet systematic review

Statins, 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase inhibitors, have proven efficacy in both lowering low-density-lipoprotein levels and preventing major coronary events, making them one of the most commonly prescribed drugs in the United States. Statins exhibit a class-wide side effect of mus...

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Bibliographic Details
Published in:Genet Med
Main Authors: Canestaro, William J., Austin, Melissa A., Thummel, Kenneth E.
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4676271/
https://ncbi.nlm.nih.gov/pubmed/24810685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gim.2014.41
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