Randomized trial of primaquine hypnozoitocidal efficacy when administered with artemisinin-combined blood schizontocides for radical cure of Plasmodium vivax in Indonesia

BACKGROUND: Safety and efficacy of primaquine against repeated attacks of Plasmodium vivax depends upon co-administered blood schizontocidal therapy in radical cure. We assessed primaquine (PQ) as hypnozoitocide when administered with dihydroartemisinin-piperaquine (Eurartesim®, DHA-PP) or artesunat...

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Veröffentlicht in:BMC Med
Hauptverfasser: Nelwan, Erni J., Ekawati, Lenny L., Tjahjono, Bagus, Setiabudy, Rianto, Sutanto, Inge, Chand, Krisin, Ekasari, Tyas, Djoko, Dwi, Basri, Hasan, Taylor, W. Robert, Duparc, Stephan, Subekti, Decy, Elyazar, Iqbal, Noviyanti, Rintis, Sudoyo, Herawati, Baird, J. Kevin
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4676167/
https://ncbi.nlm.nih.gov/pubmed/26654101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12916-015-0535-9
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