Functional relevance of a six mesenchymal gene signature in epithelial-mesenchymal transition (EMT) reversal by the triple angiokinase inhibitor, nintedanib (BIBF1120)

Epithelial-mesenchymal transition (EMT), a crucial mechanism in carcinoma progression, describes the process whereby epithelial cells lose their apico-basal polarity and junctional complexes and acquire a mesenchymal-like morphology. Several markers are considered to be authentic indicators of an ep...

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Publicado en:Oncotarget
Autores principales: Huang, Ruby Yun-Ju, Kuay, Kuee Theng, Tan, Tuan Zea, Asad, Mohammad, Tang, Hei Mui, Ng, Aloysius Hsien Chun, Ye, Jieru, Chung, Vin Yee, Thiery, Jean Paul
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4673149/
https://ncbi.nlm.nih.gov/pubmed/26061747
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