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Overexpression of Catalase Diminishes Oxidative Cysteine Modifications of Cardiac Proteins

Reactive protein cysteine thiolates are instrumental in redox regulation. Oxidants, such as hydrogen peroxide (H(2)O(2)), react with thiolates to form oxidative post-translational modifications, enabling physiological redox signaling. Cardiac disease and aging are associated with oxidative stress wh...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Yao, Chunxiang, Behring, Jessica B., Shao, Di, Sverdlov, Aaron L., Whelan, Stephen A., Elezaby, Aly, Yin, Xiaoyan, Siwik, Deborah A., Seta, Francesca, Costello, Catherine E., Cohen, Richard A., Matsui, Reiko, Colucci, Wilson S., McComb, Mark E., Bachschmid, Markus M.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4671598/
https://ncbi.nlm.nih.gov/pubmed/26642319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0144025
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