Overexpression of Catalase Diminishes Oxidative Cysteine Modifications of Cardiac Proteins

Reactive protein cysteine thiolates are instrumental in redox regulation. Oxidants, such as hydrogen peroxide (H(2)O(2)), react with thiolates to form oxidative post-translational modifications, enabling physiological redox signaling. Cardiac disease and aging are associated with oxidative stress wh...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Yao, Chunxiang, Behring, Jessica B., Shao, Di, Sverdlov, Aaron L., Whelan, Stephen A., Elezaby, Aly, Yin, Xiaoyan, Siwik, Deborah A., Seta, Francesca, Costello, Catherine E., Cohen, Richard A., Matsui, Reiko, Colucci, Wilson S., McComb, Mark E., Bachschmid, Markus M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4671598/
https://ncbi.nlm.nih.gov/pubmed/26642319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0144025
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