Jagged 1 rescues the Duchenne muscular dystrophy phenotype

Duchenne muscular dystrophy, caused by mutations at the dystrophin gene, is the most common form of Muscular Dystrophy. There is no cure for DMD and current therapeutic approaches to restore dystrophin expression are only partially effective. The absence of dystrophin in muscle results in dysregulat...

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Foilsithe in:Cell
Main Authors: Vieira, Natassia M., Elvers, Ingegerd, Alexander, Matthew S., Moreira, Yuri B., Eran, Alal, Gomes, Juliana P., Marshall, Jamie L., Karlsson, Elinor K., Verjovski-Almeida, Sergio, Lindblad-Toh, Kerstin, Kunkel, Louis M., Zatz, Mayana
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2015
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4668935/
https://ncbi.nlm.nih.gov/pubmed/26582133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.10.049
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