Checkpoint kinase 2 (CHK2) negatively regulates androgen sensitivity and prostate cancer cell growth

Prostate cancer (PCa) is the second leading cause of cancer death in American men, and curing metastatic disease remains a significant challenge. Nearly all patients with disseminated PCa initially respond to androgen deprivation therapy (ADT), but virtually all patient will relapse and develop incu...

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Vydáno v:Cancer Res
Hlavní autoři: Ta, Huy Q, Ivey, Melissa L, Frierson, Henry F, Conaway, Mark R, Dziegielewski, Jaroslaw, Larner, James M, Gioeli, Daniel
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4668217/
https://ncbi.nlm.nih.gov/pubmed/26573794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-0224
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