Carregant...

Asymmetric Synthesis of β-Amino Amides by Catalytic Enantioconvergent 2-Aza-Cope Rearrangement

Dynamic kinetic resolutions of α-stereogenic-β-formyl amides in asymmetric 2-aza-Cope rearrangements are described. Chiral phosphoric acids catalyze this rare example of a non-hydrogenative DKR of a β-oxo acid derivative. The [3,3]-rearrangement occurs with high diastereo- and enantiocontrol, formin...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:J Am Chem Soc
Autors principals: Goodman, C. Guy, Johnson, Jeffrey S.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4661081/
https://ncbi.nlm.nih.gov/pubmed/26561873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b09593
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!