Attenuation of myocardial fibrosis with curcumin is mediated by modulating expression of angiotensin II AT1/AT2 receptors and ACE2 in rats

Curcumin is known to improve cardiac function by balancing degradation and synthesis of collagens after myocardial infarction. This study tested the hypothesis that inhibition of myocardial fibrosis by curcumin is associated with modulating expression of angiotensin II (Ang II) receptors and angiote...

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Bibliographic Details
Published in:Drug Des Devel Ther
Main Authors: Pang, Xue-Fen, Zhang, Li-Hui, Bai, Feng, Wang, Ning-Ping, Garner, Ron E, McKallip, Robert J, Zhao, Zhi-Qing
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2015
Subjects:
Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4651552/
https://ncbi.nlm.nih.gov/pubmed/26648693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S95333
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